Tioguanine
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB00352 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 74 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | chronic myelogenous leukemia, BCR-ABL1 positive | KG + DL |
| 2 | upper aerodigestive tract neoplasm | KG + DL |
| 3 | unclassified myelodysplastic syndrome | KG + DL |
| 4 | partial deletion of the long arm of chromosome 5 | KG + DL |
| 5 | refractory cytopenia of childhood | KG + DL |
| 6 | aregenerative anemia | KG + DL |
| 7 | severe congenital hypochromic anemia with ringed sideroblasts | KG + DL |
| 8 | blast phase chronic myelogenous leukemia, BCR-ABL1 positive | KG + DL |
| 9 | osteoclastic giant cell tumor of pancreas | KG + DL |
| 10 | solid pseudopapillary carcinoma of pancreas | KG + DL |
| 11 | acute lymphoblastic/lymphocytic leukemia | KG + DL |
| 12 | primary pulmonary lymphoma | KG + DL |
| 13 | pancreatic carcinoma with mixed differentiation | KG + DL |
| 14 | mixed ductal-endocrine carcinoma of pancreas | KG + DL |
| 15 | pulmonary blastoma | KG + DL |
| 16 | pancreatic intraductal papillary-mucinous carcinoma | KG + DL |
| 17 | pancreatic adenocarcinoma | KG + DL |
| 18 | well-differentiated fetal adenocarcinoma of the lung | KG + DL |
| 19 | malignant exocrine pancreas neoplasm | KG + DL |
| 20 | pancreatic signet ring cell adenocarcinoma | KG + DL |
| 21 | undifferentiated pancreatic carcinoma | KG + DL |
| 22 | bulbar polio | KG + DL |
| 23 | pregerminal center chronic lymphocytic leukemia/small lymphocytic lymphoma | KG + DL |
| 24 | chronic lymphocytic leukemia/small lymphocytic lymphoma with immunoglobulin heavy chain variable-region gene somatic hypermutation | KG + DL |
| 25 | pancreatic intraductal papillary-mucinous neoplasm | KG + DL |
| 26 | small cell lung carcinoma | KG + DL |
| 27 | pancreatic acinar cell cystadenocarcinoma | KG + DL |
| 28 | myelodysplastic syndrome | KG + DL |
| 29 | pancreatic serous cystadenocarcinoma | KG + DL |
| 30 | 5q35 microduplication syndrome | KG + DL |
| 31 | pancreatic mucinous cystadenocarcinoma | KG + DL |
| 32 | ganglioneuroblastoma (disease) | KG + DL |
| 33 | head and neck cancer | KG + DL |
| 34 | bladder exstrophy-epispadias-cloacal exstrophy complex | KG + DL |
| 35 | retroperitoneal neoplasm | KG + DL |
| 36 | vertebral anomalies and variable endocrine and T-cell dysfunction | KG + DL |
| 37 | salivary gland type cancer of the breast | KG + DL |
| 38 | neuralgic amyotrophy | KG + DL |
| 39 | breast papillomatosis | KG + DL |
| 40 | bladder exstrophy (disease) | KG + DL |
| 41 | colloid carcinoma of the pancreas | KG + DL |
| 42 | bladder transitional cell carcinoma | KG + DL |
| 43 | giant adenofibroma of the breast | KG + DL |
| 44 | benign neoplasm of male breast | KG + DL |
| 45 | diabetic mastopathy | KG + DL |
| 46 | intraductal breast papillomatosis | KG + DL |
| 47 | breast lipoma | KG + DL |
| 48 | fibroepithelial neoplasm | KG + DL |
| 49 | benign eccrine breast spiradenoma | KG + DL |
| 50 | subareolar duct papillomatosis | KG + DL |
(Showing top 50 of 74 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.