Lapatinib
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB01259 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 62 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | dermatofibrosarcoma protuberans | KG + DL |
| 2 | fibroblastic neoplasm | KG + DL |
| 3 | conventional fibrosarcoma | KG + DL |
| 4 | kidney fibrosarcoma | KG + DL |
| 5 | cysticercosis | KG + DL |
| 6 | heart fibrosarcoma | KG + DL |
| 7 | low grade fibromyxoid sarcoma | KG + DL |
| 8 | Plasmodium falciparum malaria | KG + DL |
| 9 | coenurosis | KG + DL |
| 10 | lymphangiomyoma | KG + DL |
| 11 | benign PEComa | KG + DL |
| 12 | uterine corpus perivascular epithelioid cell tumor | KG + DL |
| 13 | autosomal recessive familial Mediterranean fever | KG + DL |
| 14 | liver fibrosarcoma | KG + DL |
| 15 | cutaneous undifferentiated pleomorphic sarcoma | KG + DL |
| 16 | central nervous system fibrosarcoma | KG + DL |
| 17 | normal breast-like subtype of breast carcinoma | KG + DL |
| 18 | progesterone-receptor positive breast cancer | KG + DL |
| 19 | progesterone-receptor negative breast cancer | KG + DL |
| 20 | breast tumor luminal A or B | KG + DL |
| 21 | cutaneous leiomyosarcoma (disease) | KG + DL |
| 22 | Marfan syndrome | KG + DL |
| 23 | gallbladder leiomyosarcoma | KG + DL |
| 24 | situs inversus | KG + DL |
| 25 | lymphangioleiomyomatosis | KG + DL |
| 26 | diaphragmatic or abdominal wall malformation | KG + DL |
| 27 | paralytic facial malformation | KG + DL |
| 28 | hypoglossia/aglossia | KG + DL |
| 29 | external auditory canal aplasia/hypoplasia | KG + DL |
| 30 | congenital limb malformation | KG + DL |
| 31 | digestive tract malformation | KG + DL |
| 32 | breast fibrosarcoma | KG + DL |
| 33 | bone fibrosarcoma | KG + DL |
| 34 | malformation syndrome with hamartosis | KG + DL |
| 35 | facial cleft | KG + DL |
| 36 | cutis laxa - Marfanoid syndrome | KG + DL |
| 37 | tuberous sclerosis | KG + DL |
| 38 | lung PEComa | KG + DL |
| 39 | pseudodiastrophic dysplasia | KG + DL |
| 40 | synovium cancer | KG + DL |
| 41 | heart position anomaly | KG + DL |
| 42 | cleft lip with or without cleft palate | KG + DL |
| 43 | cranial malformation | KG + DL |
| 44 | laterality defects, autosomal dominant | KG + DL |
| 45 | obsolete Marfan syndrome type 2 | KG + DL |
| 46 | familial Mediterranean fever, autosomal dominant | KG + DL |
| 47 | tenosynovial giant cell tumor | KG + DL |
| 48 | situs ambiguus | KG + DL |
| 49 | fusariosis | KG + DL |
| 50 | familial caudal dysgenesis | KG + DL |
(Showing top 50 of 62 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.