Colchicine
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB01394 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 42 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | Plasmodium falciparum malaria | KG + DL |
| 2 | familial Mediterranean fever, autosomal dominant | KG + DL |
| 3 | dermatofibrosarcoma protuberans | KG + DL |
| 4 | primary immunodeficiency due to a genetic defect in innate immunity | KG + DL |
| 5 | sitosterolemia | KG + DL |
| 6 | Smouldering systemic mastocytosis | KG + DL |
| 7 | systemic mastocytosis | KG + DL |
| 8 | lymphoadenopathic mastocytosis with eosinophilia | KG + DL |
| 9 | hemoglobin H disease | KG + DL |
| 10 | blepharo-cheilo-odontic syndrome | KG + DL |
| 11 | benign PEComa | KG + DL |
| 12 | dominant beta-thalassemia | KG + DL |
| 13 | multiple endocrine neoplasia | KG + DL |
| 14 | uterine corpus perivascular epithelioid cell tumor | KG + DL |
| 15 | lymphangiomyoma | KG + DL |
| 16 | fibroblastic neoplasm | KG + DL |
| 17 | conventional fibrosarcoma | KG + DL |
| 18 | kidney fibrosarcoma | KG + DL |
| 19 | trigeminal nerve neoplasm | KG + DL |
| 20 | low grade fibromyxoid sarcoma | KG + DL |
| 21 | heart fibrosarcoma | KG + DL |
| 22 | branchiooculofacial syndrome | KG + DL |
| 23 | lymphangioleiomyomatosis | KG + DL |
| 24 | trigeminal neuralgia | KG + DL |
| 25 | autoinflammatory syndrome with immune deficiency | KG + DL |
| 26 | spherocytosis | KG + DL |
| 27 | xanthoma (disease) | KG + DL |
| 28 | X-linked lymphoproliferative disease due to SH2D1A deficiency | KG + DL |
| 29 | thalassemia, beta+, silent allele | KG + DL |
| 30 | familial glomangioma | KG + DL |
| 31 | mesenchymal cell neoplasm | KG + DL |
| 32 | acute erythroid leukemia | KG + DL |
| 33 | A20 haploinsufficiency | KG + DL |
| 34 | spondyloepiphyseal dysplasia tarda, autosomal dominant | KG + DL |
| 35 | recessive X-linked ichthyosis | KG + DL |
| 36 | lung PEComa | KG + DL |
| 37 | immune dysregulation with inflammatory bowel disease | KG + DL |
| 38 | hereditary persistence of fetal hemoglobin-beta-thalassemia syndrome | KG + DL |
| 39 | liver fibrosarcoma | KG + DL |
| 40 | periodic fever-infantile enterocolitis-autoinflammatory syndrome | KG + DL |
| 41 | beta thalassemia | KG + DL |
| 42 | Hb Bart’s hydrops fetalis | KG + DL |
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.