Rufinamide
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB06201 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 21 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | febrile infection-related epilepsy syndrome | KG + DL |
| 2 | perioral myoclonia with absences | KG + DL |
| 3 | cryptogenic late-onset epileptic spasms | KG + DL |
| 4 | photosensitive occipital lobe epilepsy | KG + DL |
| 5 | atypical childhood epilepsy with centrotemporal spikes | KG + DL |
| 6 | trigeminal nerve neoplasm | KG + DL |
| 7 | benign occipital epilepsy | KG + DL |
| 8 | childhood onset epileptic encephalopathy | KG + DL |
| 9 | early-onset epileptic encephalopathy and intellectual disability due to GRIN2A mutation | KG + DL |
| 10 | renal-hepatic-pancreatic dysplasia | KG + DL |
| 11 | polycystic kidney disease 3 with or without polycystic liver disease | KG + DL |
| 12 | Joubert syndrome with renal defect | KG + DL |
| 13 | karyomegalic interstitial nephritis | KG + DL |
| 14 | thoracic malformation | KG + DL |
| 15 | adult familial nephronophthisis-spastic quadriparesia syndrome | KG + DL |
| 16 | early onset absence epilepsy | KG + DL |
| 17 | acute encephalopathy with biphasic seizures and late reduced diffusion | KG + DL |
| 18 | trigeminal neuralgia | KG + DL |
| 19 | familial hemiplegic migraine | KG + DL |
| 20 | polycystic kidney disease | KG + DL |
| 21 | polymicrogyria with optic nerve hypoplasia | KG + DL |
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.