Midostaurin
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB06595 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 34 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | familial thrombocytosis | KG + DL |
| 2 | reactive thrombocytosis | KG + DL |
| 3 | metastatic melanoma | KG + DL |
| 4 | inverse Klippel-Trenaunay syndrome | KG + DL |
| 5 | thrombocythemia | KG + DL |
| 6 | non-cutaneous melanoma | KG + DL |
| 7 | epithelioid cell melanoma | KG + DL |
| 8 | eyelid melanoma | KG + DL |
| 9 | scrotum melanoma | KG + DL |
| 10 | lentigo maligna melanoma | KG + DL |
| 11 | CDK4 linked melanoma | KG + DL |
| 12 | superficial spreading melanoma | KG + DL |
| 13 | acral lentiginous melanoma (disease) | KG + DL |
| 14 | amelanotic skin melanoma | KG + DL |
| 15 | balloon cell malignant melanoma | KG + DL |
| 16 | nodular malignant melanoma | KG + DL |
| 17 | malignant melanoma of the mucosa | KG + DL |
| 18 | choroideremia | KG + DL |
| 19 | bulbar polio | KG + DL |
| 20 | choroidal dystrophy, central areolar | KG + DL |
| 21 | great vessel cancer | KG + DL |
| 22 | 5q35 microduplication syndrome | KG + DL |
| 23 | neuralgic amyotrophy | KG + DL |
| 24 | amyotrophic neuralgia | KG + DL |
| 25 | polyclonal hypergammaglobulinemia | KG + DL |
| 26 | intestinal obstruction in the newborn due to guanylate cyclase 2C deficiency | KG + DL |
| 27 | monoclonal paraproteinemia disease | KG + DL |
| 28 | myelodysplastic/myeloproliferative disease | KG + DL |
| 29 | acute myeloid leukemia and myelodysplastic syndromes related to alkylating agent | KG + DL |
| 30 | acute myeloid leukemia and myelodysplastic syndromes related to radiation | KG + DL |
| 31 | chronic myelogenous leukemia, BCR-ABL1 positive | KG + DL |
| 32 | poliomyelitis | KG + DL |
| 33 | uterine corpus myxoid leiomyosarcoma | KG + DL |
| 34 | uterine corpus epithelioid leiomyosarcoma | KG + DL |
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.