Ruxolitinib
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB08877 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | uterine corpus perivascular epithelioid cell tumor | KG + DL |
| 2 | benign PEComa | KG + DL |
| 3 | lymphangiomyoma | KG + DL |
| 4 | lymphangioleiomyomatosis | KG + DL |
| 5 | liposarcoma | KG + DL |
| 6 | familial rhabdoid tumor | KG + DL |
| 7 | lung PEComa | KG + DL |
| 8 | ovarian myxoid liposarcoma | KG + DL |
| 9 | hemophagocytic syndrome associated with an infection | KG + DL |
| 10 | acquired hemophagocytic lymphohistiocytosis associated with malignant disease | KG + DL |
| 11 | thrombocytopenia | KG + DL |
| 12 | dermatofibrosarcoma protuberans | KG + DL |
| 13 | hereditary thrombocytopenia with normal platelets | KG + DL |
| 14 | marcothrombocytopenia with mitral valve insufficiency | KG + DL |
| 15 | transient neonatal thrombocytopenia | KG + DL |
| 16 | dense granule disease | KG + DL |
| 17 | neurolymphomatosis | KG + DL |
| 18 | rhabdoid tumor | KG + DL |
| 19 | heart fibrosarcoma | KG + DL |
| 20 | fibroblastic neoplasm | KG + DL |
| 21 | kidney fibrosarcoma | KG + DL |
| 22 | vulva sarcoma | KG + DL |
| 23 | conventional fibrosarcoma | KG + DL |
| 24 | low grade fibromyxoid sarcoma | KG + DL |
| 25 | relapsing-remitting multiple sclerosis | KG + DL |
| 26 | Budd-Chiari syndrome | KG + DL |
| 27 | liver fibrosarcoma | KG + DL |
| 28 | spindle cell liposarcoma | KG + DL |
| 29 | familial generalized lentiginosis | KG + DL |
| 30 | hepatic vein thrombosis | KG + DL |
| 31 | bone fibrosarcoma | KG + DL |
| 32 | leukonychia totalis-acanthosis-nigricans-like lesions-abnormal hair syndrome | KG + DL |
| 33 | non-syndromic syndactyly | KG + DL |
| 34 | congenital multiple café-au-lait macules-increased sister chromatid exchange syndrome | KG + DL |
| 35 | acromelanosis | KG + DL |
| 36 | myeloproliferative neoplasm, unclassifiable | KG + DL |
| 37 | peripheral nerve schwannoma | KG + DL |
| 38 | chronic neutrophilic leukemia | KG + DL |
| 39 | hemophagocytic syndrome | KG + DL |
| 40 | sympathetic neurilemmoma | KG + DL |
| 41 | schwannoma of twelfth cranial nerve | KG + DL |
| 42 | Dedifferentiated liposarcoma | KG + DL |
| 43 | trigeminal schwannoma | KG + DL |
| 44 | microcystic/reticular schwannoma | KG + DL |
| 45 | gastrocutaneous syndrome | KG + DL |
| 46 | Moynahan syndrome | KG + DL |
| 47 | atypical lipomatous tumor | KG + DL |
| 48 | myeloid neoplasm associated with PDGFRB rearrangement | KG + DL |
| 49 | myeloid neoplasm associated with FGFR1 rearrangement | KG + DL |
| 50 | hepatic veno-occlusive disease | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.