Ponatinib
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB08901 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 58 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | fibromatosis, gingival | KG + DL |
| 2 | liposarcoma | KG + DL |
| 3 | inclusion body myopathy with early-onset Paget disease with or without frontotemporal dementia | KG + DL |
| 4 | ovarian myxoid liposarcoma | KG + DL |
| 5 | hamartoma of lung | KG + DL |
| 6 | fibroma of lung | KG + DL |
| 7 | junctional epidermolysis bullosa | KG + DL |
| 8 | Leukomelanoderma-infantilism-intellectual disability-hypodontia-hypotrichosis syndrome | KG + DL |
| 9 | lung benign neoplasm | KG + DL |
| 10 | lung hilum carcinoma | KG + DL |
| 11 | Ewing sarcoma | KG + DL |
| 12 | familial thrombocytosis | KG + DL |
| 13 | lung germ cell tumor | KG + DL |
| 14 | pulmonary sulcus neoplasm | KG + DL |
| 15 | reactive thrombocytosis | KG + DL |
| 16 | ovarioleukodystrophy | KG + DL |
| 17 | lung cancer | KG + DL |
| 18 | junctional epidermolysis bullosa, non-Herlitz type | KG + DL |
| 19 | dehydratase deficiency | KG + DL |
| 20 | inverse Klippel-Trenaunay syndrome | KG + DL |
| 21 | myeloid leukemia | KG + DL |
| 22 | pregerminal center chronic lymphocytic leukemia/small lymphocytic lymphoma | KG + DL |
| 23 | chronic lymphocytic leukemia/small lymphocytic lymphoma with immunoglobulin heavy chain variable-region gene somatic hypermutation | KG + DL |
| 24 | thrombocythemia | KG + DL |
| 25 | ganglioneuroblastoma (disease) | KG + DL |
| 26 | acute lymphoblastic/lymphocytic leukemia | KG + DL |
| 27 | vertebral anomalies and variable endocrine and T-cell dysfunction | KG + DL |
| 28 | retroperitoneal neoplasm | KG + DL |
| 29 | dermatofibrosarcoma protuberans | KG + DL |
| 30 | bone sarcoma | KG + DL |
| 31 | neuroblastoma | KG + DL |
| 32 | vulva sarcoma | KG + DL |
| 33 | amyotrohpic lateral sclerosis type 22 | KG + DL |
| 34 | Waldenstrom macroglobulinemia | KG + DL |
| 35 | orbit sarcoma | KG + DL |
| 36 | synovial chondromatosis | KG + DL |
| 37 | uterine corpus sarcoma | KG + DL |
| 38 | extracutaneous mastocytoma | KG + DL |
| 39 | amyotrophic lateral sclerosis, susceptibility to | KG + DL |
| 40 | giant cell tumor of soft tissue | KG + DL |
| 41 | heart fibrosarcoma | KG + DL |
| 42 | sarcoma, avian | KG + DL |
| 43 | axial spondylometaphyseal dysplasia | KG + DL |
| 44 | kidney fibrosarcoma | KG + DL |
| 45 | fibroblastic neoplasm | KG + DL |
| 46 | great vessel cancer | KG + DL |
| 47 | amyotrophic lateral sclerosis | KG + DL |
| 48 | conventional fibrosarcoma | KG + DL |
| 49 | familial rhabdoid tumor | KG + DL |
| 50 | low grade fibromyxoid sarcoma | KG + DL |
(Showing top 50 of 58 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.