Osimertinib
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB09330 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | thrombocytopenia | KG + DL |
| 2 | heart neoplasm | KG + DL |
| 3 | thrombotic disease | KG + DL |
| 4 | heart conduction disease | KG + DL |
| 5 | marcothrombocytopenia with mitral valve insufficiency | KG + DL |
| 6 | hereditary thrombocytopenia with normal platelets | KG + DL |
| 7 | cardiovascular disease | KG + DL |
| 8 | transient neonatal thrombocytopenia | KG + DL |
| 9 | dense granule disease | KG + DL |
| 10 | heart disease | KG + DL |
| 11 | heart valve disease | KG + DL |
| 12 | Laubry-Pezzi syndrome | KG + DL |
| 13 | congenital anomaly of ventricular septum | KG + DL |
| 14 | interventricular septum aneurysm | KG + DL |
| 15 | Pierre Robin syndrome associated with a chromosomal anomaly | KG + DL |
| 16 | genetic syndromic Pierre Robin syndrome | KG + DL |
| 17 | rheumatoid arthritis | KG + DL |
| 18 | Jeune syndrome situs inversus | KG + DL |
| 19 | orofacial clefting syndrome | KG + DL |
| 20 | disorder of fucoglycosan synthesis | KG + DL |
| 21 | partial deletion of the long arm of chromosome 7 | KG + DL |
| 22 | amyotrophic lateral sclerosis | KG + DL |
| 23 | partial deletion of the long arm of chromosome 22 | KG + DL |
| 24 | pulmonary valve disease | KG + DL |
| 25 | pericardium disease | KG + DL |
| 26 | mitral valve disease | KG + DL |
| 27 | patent ductus arteriosus-bicuspid aortic valve-hand anomalies syndrome | KG + DL |
| 28 | cardiac ventricle disease | KG + DL |
| 29 | amyotrohpic lateral sclerosis type 22 | KG + DL |
| 30 | amyotrophic lateral sclerosis, susceptibility to | KG + DL |
| 31 | white forelock with malformations | KG + DL |
| 32 | Mills syndrome | KG + DL |
| 33 | microcephaly-cardiac defect-lung malsegmentation syndrome | KG + DL |
| 34 | cardiac anomalies-heterotaxy syndrome | KG + DL |
| 35 | heart aneurysm | KG + DL |
| 36 | carcinoid heart disease | KG + DL |
| 37 | myocardial rupture | KG + DL |
| 38 | cor biloculare | KG + DL |
| 39 | axial spondylometaphyseal dysplasia | KG + DL |
| 40 | aortopulmonary window | KG + DL |
| 41 | brachydactyly-syndactyly syndrome | KG + DL |
| 42 | myocardial disorder | KG + DL |
| 43 | bilateral parasagittal parieto-occipital polymicrogyria | KG + DL |
| 44 | female breast carcinoma | KG + DL |
| 45 | multiple endocrine neoplasia | KG + DL |
| 46 | vein disease | KG + DL |
| 47 | trichomegaly-retina pigmentary degeneration-dwarfism syndrome | KG + DL |
| 48 | tarp syndrome | KG + DL |
| 49 | lethal arthrogryposis-anterior horn cell disease syndrome | KG + DL |
| 50 | monomelic amyotrophy | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.