Ravulizumab
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB11580 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | autosomal recessive severe congenital neutropenia due to G6PC3 deficiency | KG + DL |
| 2 | cyclic hematopoiesis | KG + DL |
| 3 | primary hyperoxaluria | KG + DL |
| 4 | severe congenital neutropenia | KG + DL |
| 5 | autosomal recessive severe congenital neutropenia due to CXCR2 deficiency | KG + DL |
| 6 | primary immunodeficiency syndrome due to p14 deficiency | KG + DL |
| 7 | pseudo-von Willebrand disease | KG + DL |
| 8 | X-linked severe congenital neutropenia | KG + DL |
| 9 | primary release disorder of platelets | KG + DL |
| 10 | megaloblastic anemia (disease) | KG + DL |
| 11 | autosomal recessive severe congenital neutropenia due to JAGN1 deficiency | KG + DL |
| 12 | cold agglutinin disease | KG + DL |
| 13 | autosomal recessive severe congenital neutropenia due to CSF3R deficiency | KG + DL |
| 14 | adult idiopathic neutropenia | KG + DL |
| 15 | congenital neutropenia-myelofibrosis-nephromegaly syndrome | KG + DL |
| 16 | Barth syndrome | KG + DL |
| 17 | Glanzmann thrombasthenia | KG + DL |
| 18 | primary CD59 deficiency | KG + DL |
| 19 | proteinuria | KG + DL |
| 20 | constitutional neutropenia | KG + DL |
| 21 | neonatal autoimmune hemolytic anemia | KG + DL |
| 22 | mixed-type autoimmune hemolytic anemia | KG + DL |
| 23 | drug-induced autoimmune hemolytic anemia | KG + DL |
| 24 | Peyronie disease | KG + DL |
| 25 | Kostmann syndrome | KG + DL |
| 26 | Wilson disease | KG + DL |
| 27 | disorder of mineral absorption and transport | KG + DL |
| 28 | hereditary hemochromatosis | KG + DL |
| 29 | hereditary hypercarotenemia and vitamin A deficiency | KG + DL |
| 30 | disorder of phenylalanine metabolism | KG + DL |
| 31 | velo-facial-skeletal syndrome | KG + DL |
| 32 | familial isolated deficiency of vitamin E | KG + DL |
| 33 | silent sinus syndrome | KG + DL |
| 34 | familial nasal acilia | KG + DL |
| 35 | juvenile nasopharyngeal angiofibroma (disease) | KG + DL |
| 36 | disorder of vitamin and non-protein cofactor absorption and transport | KG + DL |
| 37 | craniorhiny | KG + DL |
| 38 | phenylketonuria | KG + DL |
| 39 | maternal hyperthermia induced birth defects | KG + DL |
| 40 | fetal minoxidil syndrome | KG + DL |
| 41 | cleft lip/palate-intestinal malrotation-cardiopathy syndrome | KG + DL |
| 42 | neonatal epileptic encephalopathy due to glutaminase deficiency | KG + DL |
| 43 | mandibulofacial dysostosis-macroblepharon-macrostomia syndrome | KG + DL |
| 44 | genetic otorhinolaryngological malformation | KG + DL |
| 45 | inborn disorder of phenylalanin or tyrosine metabolism | KG + DL |
| 46 | semicircular canal dehiscence syndrome | KG + DL |
| 47 | idiopathic bilateral vestibulopathy | KG + DL |
| 48 | phenobarbital embryopathy | KG + DL |
| 49 | Bencze syndrome | KG + DL |
| 50 | fetal trimethadione syndrome | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.