Ribociclib
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB11730 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | myeloid leukemia | KG + DL |
| 2 | thrombocytopenia | KG + DL |
| 3 | marcothrombocytopenia with mitral valve insufficiency | KG + DL |
| 4 | hereditary thrombocytopenia with normal platelets | KG + DL |
| 5 | transient neonatal thrombocytopenia | KG + DL |
| 6 | dense granule disease | KG + DL |
| 7 | female breast carcinoma | KG + DL |
| 8 | multiple endocrine neoplasia | KG + DL |
| 9 | HIV infectious disease | KG + DL |
| 10 | heart neoplasm | KG + DL |
| 11 | platelet storage pool deficiency | KG + DL |
| 12 | plasma cell myeloma | KG + DL |
| 13 | collagenopathy | KG + DL |
| 14 | lymphocytic hypereosinophilic syndrome | KG + DL |
| 15 | cardiovascular disease | KG + DL |
| 16 | heart valve disease | KG + DL |
| 17 | feline acquired immunodeficiency syndrome | KG + DL |
| 18 | simian immunodeficiency virus infection | KG + DL |
| 19 | heart conduction disease | KG + DL |
| 20 | melanoma | KG + DL |
| 21 | primary cutaneous T-cell lymphoma | KG + DL |
| 22 | liposarcoma | KG + DL |
| 23 | indolent plasma cell myeloma | KG + DL |
| 24 | mycotic corneal ulcer | KG + DL |
| 25 | congenital anomaly of ventricular septum | KG + DL |
| 26 | neurodevelopmental disorder with ataxic gait, absent speech, and decreased cortical white matter | KG + DL |
| 27 | CMM7 | KG + DL |
| 28 | pediatric leptomeningeal melanoma | KG + DL |
| 29 | epithelioid cell uveal melanoma | KG + DL |
| 30 | pericardium disease | KG + DL |
| 31 | hypereosinophilic syndrome | KG + DL |
| 32 | ovarian myxoid liposarcoma | KG + DL |
| 33 | vulvar melanoma (disease) | KG + DL |
| 34 | cardiac ventricle disease | KG + DL |
| 35 | patent ductus arteriosus-bicuspid aortic valve-hand anomalies syndrome | KG + DL |
| 36 | white forelock with malformations | KG + DL |
| 37 | nipple carcinoma | KG + DL |
| 38 | microcephaly-cardiac defect-lung malsegmentation syndrome | KG + DL |
| 39 | tarp syndrome | KG + DL |
| 40 | cor biloculare | KG + DL |
| 41 | heart aneurysm | KG + DL |
| 42 | cardiac anomalies-heterotaxy syndrome | KG + DL |
| 43 | carcinoid heart disease | KG + DL |
| 44 | myocardial rupture | KG + DL |
| 45 | cardiovascular cancer | KG + DL |
| 46 | neuroblastoma | KG + DL |
| 47 | breast carcinoma by gene expression profile | KG + DL |
| 48 | bilateral breast carcinoma | KG + DL |
| 49 | ganglioneuroblastoma (disease) | KG + DL |
| 50 | estrogen-receptor negative breast cancer | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.