Apalutamide
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB11901 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 47 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | prostate cancer/brain cancer susceptibility | KG + DL |
| 2 | prostate leiomyoma | KG + DL |
| 3 | Brenner tumor | KG + DL |
| 4 | benign reproductive system neoplasm | KG + DL |
| 5 | fibroma of prostate | KG + DL |
| 6 | prostate phyllodes tumor | KG + DL |
| 7 | benign neoplasm of prostate | KG + DL |
| 8 | male reproductive organ cancer | KG + DL |
| 9 | benign prostate phyllodes tumor | KG + DL |
| 10 | palmoplantar keratoderma-sclerodactyly syndrome | KG + DL |
| 11 | female breast carcinoma | KG + DL |
| 12 | peripheral neuropathy-myopathy-hoarseness-hearing loss syndrome | KG + DL |
| 13 | renal cell carcinoma (disease) | KG + DL |
| 14 | renal pelvis carcinoma | KG + DL |
| 15 | CMM7 | KG + DL |
| 16 | renal carcinoma | KG + DL |
| 17 | unclassified renal cell carcinoma | KG + DL |
| 18 | renal cell carcinoma associated with Xp11.2 translocations/TFE3 gene fusions | KG + DL |
| 19 | renal cell carcinoma associated with neuroblastoma | KG + DL |
| 20 | pediatric leptomeningeal melanoma | KG + DL |
| 21 | melanoma | KG + DL |
| 22 | epithelioid cell uveal melanoma | KG + DL |
| 23 | nonpapillary renal cell carcinoma | KG + DL |
| 24 | estrogen-receptor negative breast cancer | KG + DL |
| 25 | bilateral breast carcinoma | KG + DL |
| 26 | hormone-resistant breast carcinoma | KG + DL |
| 27 | Ehrlich tumor carcinoma | KG + DL |
| 28 | estrogen-receptor positive breast cancer | KG + DL |
| 29 | vulvar melanoma (disease) | KG + DL |
| 30 | endocrine-cerebro-osteodysplasia syndrome | KG + DL |
| 31 | childhood kidney cell carcinoma | KG + DL |
| 32 | breast carcinoma by gene expression profile | KG + DL |
| 33 | angiolipoma | KG + DL |
| 34 | chromophobe renal cell carcinoma | KG + DL |
| 35 | familial spontaneous pneumothorax | KG + DL |
| 36 | liposarcoma | KG + DL |
| 37 | diaphyseal medullary stenosis-bone malignancy syndrome | KG + DL |
| 38 | ovarian myxoid liposarcoma | KG + DL |
| 39 | Mitchell-Riley syndrome | KG + DL |
| 40 | simian immunodeficiency virus infection | KG + DL |
| 41 | feline acquired immunodeficiency syndrome | KG + DL |
| 42 | hypoplastic pancreas-intestinal atresia-hypoplastic gallbalder syndrome | KG + DL |
| 43 | sarcomatoid renal cell carcinoma | KG + DL |
| 44 | prostate neoplasm | KG + DL |
| 45 | HIV infectious disease | KG + DL |
| 46 | clear cell renal carcinoma | KG + DL |
| 47 | collecting duct carcinoma | KG + DL |
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.