Nusinersen
Basic Information
| Item | Value |
|---|---|
| DrugBank ID | DB13161 |
| Evidence Level | L5 (Computational Prediction) |
| Number of Predicted Indications | 100 |
Predicted Indications (TxGNN)
The following are potential new indications predicted by the TxGNN model. Higher scores indicate higher predicted relevance.
| # | Indication | Source |
|---|---|---|
| 1 | trichomegaly-retina pigmentary degeneration-dwarfism syndrome | KG + DL |
| 2 | acute megakaryoblastic leukemia | KG + DL |
| 3 | 5-hydroxytryptamine oxygenase regulator | KG + DL |
| 4 | Trichomonas tenax infectious disease | KG + DL |
| 5 | epilepsy, childhood absence, susceptibility to | KG + DL |
| 6 | CHILD syndrome | KG + DL |
| 7 | methemoglobinemia due to deficiency of methemoglobin reductase | KG + DL |
| 8 | Dias-Logan syndrome | KG + DL |
| 9 | feline infectious peritonitis | KG + DL |
| 10 | nephrolithiasis susceptibility caused by SLC26A1 | KG + DL |
| 11 | partial trisomy/tetrasomy of chromosome 5 | KG + DL |
| 12 | Carabelli anomaly of maxillary molar teeth | KG + DL |
| 13 | partial duplication of chromosome 6 | KG + DL |
| 14 | radial hypoplasia-triphalangeal thumbs-hypospadias-maxillary diastema syndrome | KG + DL |
| 15 | suppurative periapical periodontitis | KG + DL |
| 16 | cortisone reductase deficiency | KG + DL |
| 17 | partial duplication of chromosome 8 | KG + DL |
| 18 | Pallister-W syndrome | KG + DL |
| 19 | porcine reproductive and respiratory syndrome | KG + DL |
| 20 | Chitayat syndrome | KG + DL |
| 21 | partial duplication of chromosome 10 | KG + DL |
| 22 | hypertelorism, microtia, facial clefting syndrome | KG + DL |
| 23 | syphilitic aortitis | KG + DL |
| 24 | oculoauricular syndrome | KG + DL |
| 25 | partial duplication of chromosome 16 | KG + DL |
| 26 | electroencephalographic peculiarity: 14 and 6 per sec. positive spike phenomenon | KG + DL |
| 27 | Dyserythropoiesis, congenital, with ultrastructurally normal erythroblast heterochromatin | KG + DL |
| 28 | partial trisomy/tetrasomy of chromosome 18 | KG + DL |
| 29 | genu valgum, st. Helena familial | KG + DL |
| 30 | tarsal tunnel syndrome | KG + DL |
| 31 | blepharocheilodontic syndrome | KG + DL |
| 32 | partial duplication of chromosome 19 | KG + DL |
| 33 | fountain syndrome | KG + DL |
| 34 | porcine postweaning multisystemic wasting syndrome | KG + DL |
| 35 | Netherton syndrome | KG + DL |
| 36 | chromosome X structural anomaly | KG + DL |
| 37 | mendelian susceptibility to mycobacterial diseases due to partial STAT1 deficiency | KG + DL |
| 38 | Ureaplasma urethritis | KG + DL |
| 39 | mal de Meleda | KG + DL |
| 40 | partial duplication of chromosome X | KG + DL |
| 41 | thyroid cancer, nonmedullary | KG + DL |
| 42 | dysplasia epiphysealis hemimelica | KG + DL |
| 43 | interstitial lung disease specific to adulthood | KG + DL |
| 44 | primary ciliary dyskinesia-retinitis pigmentosa syndrome | KG + DL |
| 45 | uveoparotid fever | KG + DL |
| 46 | androgenetic alopecia | KG + DL |
| 47 | mesoblastic nephroma | KG + DL |
| 48 | hyperzincemia with functional zinc depletion | KG + DL |
| 49 | livedoid vasculopathy | KG + DL |
| 50 | focal epithelial hyperplasia of the oral mucosa | KG + DL |
(Showing top 50 of 100 predictions)
Disclaimer
These predictions are for research purposes only and do not constitute medical advice. Clinical validation is required before any clinical application.